Spurs need to chase down Aston Villa for fourth spot, while Burnley must win to avoid relegation.
On playing a team with so much on the line, Postecoglou stated: I think again I'm pretty consistent in saying that you've got to block that stuff out. What's really important that we prepare ourselves for another big challenge.
You get to this time of the year and most games are games of consequence. We're still playing for something so you don't want to fall into that trap of expecting something different other than a really tough opponent.
As you said Burnley need a result tomorrow and they've been really aggressive in approach trying to get there. If you look at the last few weeks, they've picked up results and they've been a lot more aggressive in the way they've been going about it.
I think they feel 'well we're going to go for it if we're going to have any chance of surviving'. So we're expecting a tough game but I think that from where we're at at the moment, it's much more important how we go into the game with a focus on our football."