Alexander Isak struck twice, with Bruno Guimaraes also scoring.
Howe said: "Half-time was a big moment for us because we had to re-group. It was a difficult first half because I thought Sheffield United played well. They are fighting for their lives. We knew they would come here and have a right go.
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"It was a much improved second half display and in the end we fully deserved the win. We scored at a good time (in the second half) and were devastating at times.
"He (Bruno Guimaraes) is very much part of my plans (for next season). We have to showcase what we can offer him as a football club and hope that's enough to keep him. Bruno is a special talent and scored a big goal today. Hopefully he stays with us for many years."