The 24-year-old Ukrainian has been enjoying an outstanding season this term.
Mykolenko, who initially struggled after arriving at the club, is now a mainstay for Sean Dyche.
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Per The Mail, Mykolenko will travel to see a specialist consultant on Tuesday regarding an ankle injury.
He had a nasty fall in the club's 2-0 win over Liverpool, missing their subsequent win over Brentford.
Mykolenko and the club - along with Ukraine - will determine the best next steps.