Bayern will meet Arsenal in the quarterfinals.
Tuchel said: "We certainly have the most difficult road ahead of us when we now have to play against one of the best teams in Europe. They have played consistently at the top for two years.
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"It is a homogeneous, dangerous team, they score many goals. But we will be prepared for it. We know our qualities."
Bayern goalkeeper Manuel Neuer also has great respect for Arsenal.
"It is a very strong team. It is not for nothing that they are currently number one in the Premier League. It will be two tough games and we have to show everything we can to progress.
"It will be an exciting duel, we are looking forward to the task and are happy that we can play these matches."