They are facing off against old rivals Tottenham as they bid to win the Premier League title.
However, the lead up to the game on April 28th will be very different for both teams.
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Spurs do not have a game for 15 days before that match, as they play Newcastle on April 13th.
In contrast, Arsenal boss Mikel Arteta will have to contend with FOUR matches in those 15 days.
They take on Aston Villa on April 14th, Wolves on April 20th, and Chelsea on April 23rd.
The Gunners also have a Champions League quarter final second leg against Bayern Munich on April 17th in Germany.