Morgan Gibbs-White, Ezri Konsa and Kobbie Mainoo are out of England's squad this week.
Nottingham Forest captain Gibbs-White, Aston Villa defender Konsa and Manchester United midfielder Mainoo have all been ruled out due to injury.
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Gibbs-White was injured while having a shot blocked in their 1-1 draw with Chelsea.
Konsa suffered a hamstring injury in Sunday's goalless draw with Manchester United.
And United midfielder Mainoo was forced off in the closing stages of that match.