Ratcliffe has been hammered by United fans and pundits for his management of the club and team since buying in before Christmas 2023.
Former United manager Mourinho told Sky Sports: "To be honest I don't know much about what's happening.
"I know Sir Jim Ratcliffe. I'm not saying we are big friends but we have a good relationship.
"I know him well. He invited me to his house a couple of times. I see him as a good person and a great businessman.
"Of course, I feel for some of the people that I know (losing their jobs), but hopefully it goes in the right direction."
On United manager Ruben Amorim, Mourinho admits he's a fan. The Portuguese pair are in regular contact.
"He's a good kid," the 62-year-old said. "Always very respectful to me. We had a good relationship for a few years. He knows I wish him well."