Villa are unbeaten in eight games as they travel to Craven Cottage.
Barkley said: “From my experiences over the years, sometimes after the international break, there can be a few iffy results, but the last one, we came back from being 2-0 down against Everton and won the game.
“Hopefully, against Fulham, we can get a win again and carry on with our momentum from before the break.
“We’ve gone on a bit of an unbeaten streak, which is good, and we’ve got big games coming up, so we need to maintain that."
Barkley added: “We know what we’re going to face. They’re a top side, tactically well-equipped with Marco Silva – he’s a great manager and he’s got good ways of playing.
“They’ve got a talented group, so we are expecting a challenge, but I’m sure we’ll be ready.
“I’m sure they'll be ready for us, but hopefully on the day, we’re the better team.”