Having coached Peru at the 2018 World Cup and Swedish side Eskilstuna, Solano is back in England.
It's a wonderful challenge," Solano said.
"I'm really pleased. One of the reasons I accepted is the way my ex-teammate, Steve Howard showed me the ambition of the club which is some I love.
"It will be a great opportunity to work with the local lads. I know Blyth very well. It's a very popular team in the North East. I'm very excited, with these wonderful players and the new owner, we need to to work hard, work together and get back up into National League North".
Spartans' sporting director Howard added: I am absolutely delighted my ex-teammate has decided to join Blyth Spartans as first team manager. His wealth of experience and coaching skills will be invaluable.
"I'm looking forward to working closely with Nobby to create a team that will get back to the level they should be, and ultimately bring success to the club for years to come."