The African nation will be taking on Ghana and Mali in friendly matches later in March.
The 25-year-old Osho, who came through the Reading academy, has been with Luton since 2020.
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Osho has impressed in the Premier League, playing 18 times in all competitions and scoring in pivotal games.
He netted against Arsenal and Newcastle United, while he also played in a 1-1 draw with Crystal Palace recently.
Osho will not be managed by a permanent Nigerian boss in the next meetup, as Jose Peseiro left the job.