The Reds had to take on Everton at Goodison Park in the Premier League on Wednesday night, losing 2-0.
After the game, Klopp talked about the reason behind Cody Gakpo's absence from the devastating loss.
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Pre-game, he told Sky Sports: "Not only (to keep things fresh), two of them are not available tonight.
"Diogo (Jota) is injured and Cody probably has the best excuse of all! Timing is not great, but much more important, right now they (Gakpo and his partner) are expecting a baby; now, maybe!
"So, these are two changes we had to make. And then (in) midfield (it) makes sense, the boys played together before. We need fresh legs today as much as we can. Ibou coming back, I don't know who else, I don't think it's too many besides that.
"We meet a good team, we have a good team and now we have to play good football."