However, the club are confident that he will be involved in their Premier League game at the weekend.
Manager Sean Dyche admitted the English center forward was a doubt, but hoped to have him on the pitch against Chelsea.
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Dyche relayed the information during a Thursday press-conference, stating that Calvert-Lewin's absence was a precaution.
The Toffees also have some good news with regards to Arnaut Danjuma, who should be available.
Everton are in 16th place in the Premier League, despite having received two points deductions this term.