Palace had a 59th minute lead through Eze before Spurs fought back late on to win 3-1.
On taking off the midfielder on 63 minutes, Glasner explained, Yes, Eze had his third injury this year, a muscle injury, so you have to take care because always a re-injury takes a longer time that he's out.
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It was 65 minutes, and we cannot afford to lose him for more weeks again, so this was the reason."
On a knock to Jordan Ayew, he added: "He got a hit in the first-half on his hip. He already told us at half-time he had maybe 10 or 15 minutes, but I hope and I think it's not so bad."