The Italian was not too downbeat after his team were beaten by Bournemouth.
Encisco came off the bench and could have scored on two occasions, but had to settle for a positive impact.
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Head coach De Zerbi said: Julio Enciso yesterday (Saturday) didn't work with the team.
He is working not every day. He is working with pain in the knee.
He still feels a problem and pain because if Julio feels good, Julio is one of the first XI."
On Offiah, De Zerbi added: I think he played very well.
I played with Odel Offiah and O'Mahony because Danny Welbeck couldn't play in the first XI. Julio as well.
And for another reason, because I want to see energy, strong energy, motivation on the pitch."