Atletico host the second-leg of their Champions League round 16 clash tonight.
Simeone said of Inter's captain: "Lautaro was always an extraordinary player as a boy, he has shown it in the Argentine national team and daily in Inter. He found his place that the coach also favours for his style of play and today he is among the best forwards in Europe without a doubt."
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On the returning Antoine Griezmann, he said: "I see him in the same way that his teammates see him. Obviously his entry into the team gives us more solutions and more possibilities both tactically and in the game.
"Let's hope he has the game he wants to play."
And on the home fans, Simeone added: "I can't say anything right now. Right now it's silence and accepting everything they want to give us."