Villarreal have lost defender Cristian Zapata for their Champions League clash with Manchester City.

The Colombia international, a summer signing from Udinese who has started 14 matches this season, has sprained the ligaments in his right knee and is set to miss around five weeks, according to the Primera Division club's website.

The loss of Zapata comes after Sunday's news that Cani, Marco Ruben and Marcos Senna will all be unavailable for Wednesday's clash with City after suffering injuries during Saturday's 2-0 win over Rayo Vallecano.