Sunderland boss Steve Bruce has major concerns over Connor Wickham's knee injury suffered in defeat at Manchester United.

The 18-year-old appeared to slip and twist his leg awkwardly, leaving Bruce to contemplate the loss of another player to the same injury in the last year following Fraizer Campbell (twice), Titus Bramble, Michael Turner, Craig Gordon and David Meyler.

"That's the big disappointment of the afternoon for us because we think it's a serious knee injury, and that's now seven we've had in 12 months," said the Sunderland boss.

"We hope it's not what we think it is but the signs don't look good. It's unbelievable, I've never known anything like it."