Juventus defender Jorge Andrade suffered knee ligament damage in yesterday's 2-2 draw at Roma.
The injury could leave the Portugal international out for six months and coach Claudio Ranieri said: "I fear Andrade has broken the knee ligament in his left leg.
"It is an injury he has already had in the past. His studs got caught in the turf and his leg snapped back. He is heartbroken."