Joey Barton saw red for Olympique Marseille in their 1-0 home defeat to Nancy.
The on-loan QPR midfielder was shown two yellow cards in the space of five minutes to leave OM facing an uphill struggle at the Stade Velodrome.
And an own goal from Andre Ayew capped off a miserable evening for the title hopefuls, who remain six points behind Ligue 1 leaders Paris St Germain.