Crystal Palace boss Alan Pardew says midfielder James McArthur and forward Jason Puncheon are facing lengthy spells on the sidelines, reports Sky Sports.
McArthur has an ankle problem while Puncheon is struggling with a hamstring injury and is set to be out for around four weeks.
Pardew said: "I have some disappointing news - McArthur and Puncheon are out for a long period.
"They have both been having fabulous seasons for us, so that's a significant blow.
"Yohan Cabaye should be back for Saturday [away at Swansea] and Bakary Sako and Yannick Bolasie for Spurs [FA Cup tie on February 20]."