Phil Jones and Rafael da Silva are in line to return to the Manchester United squad for the clash at Wigan Athletic.
Both have been making good progress with their recoveries and Sir Alex told MUTV they could both be involved at the DW Stadium.
"Phil could be ready and Rafa will be ready," said the boss. "We rested Robin [van Persie], Chicharito, Ryan [Giggs] and Paul [Scholes] against West Brom so we've got enough freshness to bring in.
"Wigan had a great result today [winning 3-0 at Aston Villa] - it'll be a hard game on Tuesday."